Research news

How tissue stiffness activates cancer

pere ncb new image

pere ncb new imageResearchers at IBEC have revealed how tissue rigidity activates cancer, new knowledge that could potentially lead to new strategies to impair or even halt the growth of tumours.

The scientists and their collaborators at the Georgia Institute of Technology, publishing in and on the cover of Nature Cell Biology, have identified the mechanism by which tissue stiffness activates a protein called YAP, a major oncogene. This discovery is the result of many years’ work spent studying the forces that cells apply to their surrounding tissue – forces which determine how cells proliferate, differentiate, and move, which in turn sheds light on how development, tumorigenesis or wound healing are regulated. The discovery belongs to a family of patents in place.

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Other news

IBEC signs agreement with Bioibérica


bioibericaIBEC has signed a collaboration agreement with Bioibérica S.A., a company specialised in the R&D, production and sale of biomolecules and new technologies for the pharmaceutical, veterinary and agrochemical industries. It’s the latest success story in IBEC’s active pursuit of the establishment of research projects with industry partners who share its commitment to bringing high-quality health research and technologies to market and the patient.

Together, IBEC – specifically its Nanomalaria joint unit with ISGlobal, led by Xavier Fernández-Busquets – and Bioibérica, which since its formation in 1975 has focused on the investigation and production of biomolecules extracted from animal tissue with significant biological and therapeutic properties, will explore ways of combining their expertise to achieve advances in future medicine.

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