Cellular and respiratory biomechanics

Dr. Pere Roca-Cusachs
Junior Group Leader

Ed. Hèlix | Baldiri Reixac, 15-21 | 08028 | Barcelona
T. +34 934 020 863
Email : proca

ibecbarcelona.eu

Pere Roca-Cusachs obtained his PhD in cellular biophysics in 2007 from the Medical School at the university of Barcelona. He then worked in the lab of Prof. Michael Sheetz (Department of Biological Sciences, Columbia University) as a post-doctoral researcher until 2011. In 2011, He joined the University of Barcelona as a tenure-track lecturer. In 2012, he obtained a position as junior group leader at IBEC. His research focuses on unraveling the physical and molecular mechanisms by which cells detect and respond to mechanical force.

Publications

Roca-Cusachs, P., del Rio, A., Puklin-Faucher, E., Gaultier, N., Biais, N. & Sheetz, M. (2013). Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation. PNAS.
Roca-Cusachs, P., Iskratsch, T. & Sheetz, M. P. (2012). Finding the weakest link: exploring integrin-mediated mechanical molecular pathways. J. Cell Sci., 125(13), 3025-38.
Ghassemi, S., Meacci, G., Liu, S., Gondarenko, A. A., Mathur, A., Roca-Cusachs, P., Sheetz, M. P. & Hone, J. (2012). Cells test substrate rigidity by local contractions on sub-micrometer pillars. PNAS, 109(14), 5328-33.
Gaulthier, N., Fardin, M., Roca-Cusachs, P. & Sheetz, M. (2011). Temporary increase in plasma membrane tension coordinates the activation of exocytosis and contraction during cell spreading. PNAS, 108(35), 14467-72.
Lynch, C., Gaulthier, N., Biais, N., M., L. A., Roca-Cusachs, P., Yu, C.-H. & Sheetz, M. (2011). Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions. Mol Biol Cell, 22(8), 1263–1273.

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