Injectable and fast resorbable calcium phosphate cement for body-setting bone grafts

Research group: Biomaterials, implants and tissue engineering Year: 2010
Type of Publication: Article
Authors: I. Rajzer; Oscar Castaño; Elisabeth Engel; Josep A. Planell
Journal: Journal of Materials Science: Materials in Medicine Volume: 21
Pages: 2049-2056
ISSN: 0957-4530
Note:
10.1007/s10856-010-4078-5
Abstract:
In this work a calcium phosphate (CPC)/polymer blend was developed with the advantage of being moldable and capable of in situ setting to form calcium deficient hydroxyapatite under physiological conditions in an aqueous environment at body temperature. The CPC paste consists in a mix of R cement, glycerol as a liquid phase carrier and a biodegradable hydrogel such as Polyvinyl alcohol, which acts as a binder. Microstructure and mechanical analysis shows that the CPC blend can be used as an injectable implant for low loaded applications and fast adsorption requirements. The storage for commercial distribution was also evaluated and the properties of the materials obtained do not significantly change during storage at −18°C.
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