Integrative cell and tissue dynamics

Prof. Dr. Xavier Trepat (ICREA Research Professor)
Group Leader

Edifici Hèlix | Baldiri Reixac 15-21 | 08028 | Barcelona
T. +34 934 020 265
Email : xtrepat

ibecbarcelona.eu

Xavier Trepat received a BSc in Physics in 2000 and a B.Sc in Engineering in 2001. In 2004 he obtained his PhD from the Medical School at the University of Barcelona. He then joined the Program in Molecular and Integrative Physiological Sciences at Harvard University as a postdoctoral researcher. In 2008 he became a Ramon y Cajal researcher at the University of Barcelona and the Institute for Bioengineering of Catalonia (IBEC), and in January 2011 he became an ICREA Research Professor. His research at IBEC focuses on integrative tissue dynamics and cytoskeletal mechanics.

Publications

Nocentini, S., Reginensi, D., García, S., Carulla, P., Moreno-Flores, M., Wandosell, F., Trepat, X., Bribian, A. & del Río, J. A. (2011). Myelin-associated proteins block the migration of olfactory ensheathing cells: an in vitro study using single-cell tracking and traction force microscopy. Cell Mol Life Sci, in press.
Krishnan, R., Klumpers, D., Park, C., Rajendran, K., Trepat, X., van Bezu, J., van Hinsbergh, V., Carman, C., Brain, J., Fredberg, J., Butler, J. & van Nieuw Amerongen, G. (2011). Substrate stiffening promotes endothelial monolayer disruption through enhanced physical forces. Am J Physiol Cell Physiol, 300(1), C146-C154.
Angelini, T., Hannezo, E., Trepat, X., Marquez, M., Fredberg, J. & Weitz, D. (2011). Glass-like dynamics of collective cell migration. PNAS, 108(12), 4714-9.
Tambe, D., Hardin, C., Angelini, T., Rajendran, K., Park, C., Serra-Picamal, X., Zhou, E., Zaman, M., Butler, J., Weitz, D., Fredberg, J. & Trepat, X. (2011). Collective cell guidance by cooperative intercellular forces. Nature Materials, 10, 469–475.
Angelini, T. ~., Hannezo, E., Trepat, X., Fredberg, J. ~. & Weitz, D. ~. (2010). Cell Migration Driven by Cooperative Substrate Deformation Patterns. Physical Review Letters, 104(16), 168104-+.

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