Prof. Dr.
Gorostiza, Pau
(ICREA Research Professor)
Group Leader
Edifici Hèlix | Baldiri Reixac 15-21 | 08028 | Barcelona
Email : pgorostiza

ibecbarcelona.eu
Research Topics
Mechanics and nanostructure of biomembranes / Molecular self-assembling / Electrochemical STM-STS / Nanoelectrochemistry / Optical switches and protein nanoengineering
The group’s research focuses on developing nanoscale tools to study biological systems. These tools include instrumentation based on proximity probes, such as electrochemical tunnelling microscopy and spectroscopy that is being applied to the study of metal oxides and redox proteins. Another set of nanotools that we are developing is based on molecular actuators that can be switched with light, such as azobenzene, which can be chemically attached to biomolecules in order to optically
control their activity.
Prof. Dr. Sanz, Fausto Group Leader
Dept. Química Física | Universitat de Barcelona | Martí i Franquès 1 | 08028 | Barcelona
Email: fsanz@ub.edu

Crystal structure of redox protein azurin (Protein Data Bank entry: 1AZU) displaying its solvent accessible surface (gold) superimposed on the tertiary structure (rainbow) and a red sphere indicating the copper ion. When an atomically flat gold electrode is coated with azurin, the protein can be imaged under potentiostatic control by electrochemical tunneling microscopy (3D rendering of a 100x100nm2 area shown in blue), and its electron transfer properties can be investigated by current-distance spectroscopy (Juan Manuel Artés et al., ACS Nano 2011).

Light-activated glutamate receptor based on the photoisomerizable tethered ligand MAG (in yellow). P. Gorostiza & E. Y. Isacoff (2007), Mol. Biosyst. 3: 686-704.
7/07/2011
Nanoprobes and Nanoswitches group leader and ICREA professor Pau Gorostiza is featured in an interview in Recercat, the online newsletter of the Commission for Universities and Research of the Ministry of Economy and Knowledge.
28/03/2011
IBEC researchers have found a way to measure the rate of electron transfer (ET) – an important process which is essential in many chemical and biological processes such as cellular respiration and photosynthesis – at the single-molecule level.
02/03/2011
Flick a switch, turn a knob or pull a lever and you’re operating an electromechanical device, albeit a complex one. Now an IBEC researcher and his collaborators have broken new ground with a proven concept for the first such electronic component to operate using just a single-molecule electrical contact.
21/02/2011
ICREA group leader Pau Gorostiza’s project ‘Development of light-modulated ligands for remote, non-invasive regulation of neuropathic pain’ was announced today as one of the first twenty projects to be chosen for funding by a brand new programme, RecerCaixa.
13/02/2011
Pau Gorostiza features in a short video produced by funders RecerCaixa about the project 'Development of light-modulated ligands for remote, non-invasive regulation of neuropathic pain', of which he is the coordinator.
22/10/2010
A scientific project involving IBEC researchers has received a funding boost of €475,000 from Fundació La Marató de TV3.