Translational chemistry, optical imaging and precision medicine
Marc Vendrell , University of Edinburgh
Optical imaging has revolutionised our understanding of how biological systems behave at the molecular level. In the last years, my group has developed dynamic activatable fluorophores (DYNAFLUORS) as chemical tools to image the function and activity of immune cells in disease. We have used the probes to interrogate the dynamics of biology in real time and also translated some of them for clinical applications, including first-in-human studies. My group is currently focused on creating new probes that can help us understand the roles that specific subsets of immune cells play in the tumour microenvironment and improve personalised therapeutic approaches.
Group website: www.dynafluors.co.uk
Marc Vendrell graduated in Chemistry at the University of Barcelona in 2007. He then joined the Singapore Bioimaging Consortium to work with Young-Tae Chang in the design of synthetic fluorophores for optical imaging. In 2012 he started his independent career as an MRC Academic Fellow at the University of Edinburgh and is now a Senior Lecturer in Biomedical Imaging. He has over 90 publications, including 11 patents with multiple fluorescent probes being commercialised by Merck and Biolegend and some currently undergoing clinical studies. His research has been recognised with several international awards and distinctions, including an ERC Consolidator Grant (2017), the Marcial Moreno Lectureship (2018) and the SRUK Emerging Talent Award (2019).
He has been invited to Sílvia Pujals and Lorenzo Albertazzi