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by Keyword: Agonists

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Quadri, M., Matera, C., Silnovi, Pismataro, M. C., Horenstein, N. A., Stokes, C., Papke, R. L., Dallanoce, C., (2017). Identification of ChemMedChem XXIV National Meeting in Medicinal Chemistry (NMMC 2016) , Wiley Online Library (Perugia, Spain) 12, (16), 1335-1348

Compound 11 (3-(benzyloxy)-1′-methyl-1′-azonia-4H-1′-azaspiro[isoxazole-5,3′-bicyclo[2.2.2]octane] iodide) was selected from a previous set of nicotinic ligands as a suitable model compound for the design of new silent agonists of

Keywords: Agonists, Cycloaddition, Nitrogen heterocycles, Receptors, Spiro compounds