by Keyword: Chemotopy

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Santano-Martínez, R., Leiva-González, R., Avazbeigi, M., Gutiérrez-Gálvez, A., Marco, S., (2013). Identification of molecular properties coding areas in rat's olfactory bulb by rank products Proceedings of the International Conference on Bio-Inspired Systems and Signal Processing BIOSIGNALS 2013 , SciTePress (Barcelona, Spain) , 383-387

Neural coding of chemical information is still under strong debate. It is clear that, in vertebrates, neural representation in the olfactory bulb is a key for understanding a putative odour code. To explore this code, in this work we have studied a public dataset of radio images of 2-Deoxyglucose uptake (2-DG) in the olfactory bulb of rats in response to diverse odorants using univariate pixel selection algorithms: rank-products and Mann-Whitney U (MWU) test. Initial results indicate that some chemical properties of odorants preferentially activate certain areas of the rat olfactory bulb. While non-parametric test (MWU) has difficulties to detect these regions, rank-product provides a higher power of detection.

Keywords: 2-Deoxyglucose uptake, Chemotopy, Feature selection, Odour coding, Olfaction, Olfactory bulb