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Hüttener, Mario, Paytubi, Sonia, Juárez, Antonio, (2015). Success in incorporating horizontally transferred genes: the H-NS protein Trends in Microbiology , 23, (2), 67-69

The nucleoid-associated protein H-NS silences unwanted expression of acquired foreign DNA. Ali and colleagues recently identified which horizontally-acquired genes are targeted by H-NS in Salmonella to avoid fitness loss. The reported data strengthen our view about the role of H-NS in bacterial evolution driven by horizontal gene transfer. The nucleoid-associated protein H-NS silences unwanted expression of acquired foreign DNA. Ali and colleagues recently identified which horizontally-acquired genes are targeted by H-NS in Salmonella to avoid fitness loss. The reported data strengthen our view about the role of H-NS in bacterial evolution driven by horizontal gene transfer.

Keywords: HGT, H-NS, StpA, Salmonella, SPI1