Nanobioengineering


Josep Samitier | Group Leader
David Caballero | Senior Researcher
Anna Lagunas | Senior Researcher
Mònica Mir | Senior Researcher
Margarita Alvira | Postdoctoral Researcher
Oscar Castillo | Postdoctoral Researcher
Luís Botaya | PhD Student
Roberto Paoli | PhD Student
Luís Guillermo Rigat-Brugarolas | PhD Student
Xavier Coromina | Research Assistant
Wilmer Alfonso Pardo | Research Assistant
Miriam Funes | Laboratory Technician
David Izquierdo | Laboratory Technician
Samuel Dulay | Research Technician
Judit Pérez | Masters Student
Iro Tsintzou | Masters Student

Description

The Nanobioengineering group is a truly multidisciplinary team composed by researchers coming from very diverse backgrounds (chemistry, physics, material science, electronic engineering, pharmacy and molecular biology) and working together in applying nanotechnology to the development of new biomedical systems and devices, mainly for diagnostic purposes, and integrated microfluidic devices for organ on chip.

samitier2014_0

Nanopatterning of RGD-Cys-D1 on Au(111) surfaces


The main activities of the group involve the surface functionalization of materials integrated with microfluidics systems for the study of biomolecule and cell interactions to develop Organ on Chip or for the development of new biosensors that will be integrated in lab-on-a-chip devices. The goal is to fabricate microsystems containing living cells that recapitulate tissue and organ level functions in vitro and new portable diagnosis devices that can be used as Point-of-Care systems.

The projects carried out by the group are focused on clinical and industrial problems and are related to four convergent research lines:

samitier2014_2

Neuro Muscular Junction formation in compartmentalized microfluidic devices

Biosensors and Lab-on-a-chip for clinical diagnosis and food safety applications

  • DNA sensors and platform arrays for cancer biomarker detection
  • Antibody-based sensors for pathogenic microorganisms’ detection
  • Sensor array for in-vivo Ischemia Monitoring
  • Sensors to mimic the chemical detection of plant roots for robotic applications.
  • Microfluidic chip for reagent handling in POC diagnosis devices
  • Microfluidic chip using hydrodynamic focusing for bacteria counting and sorting
samitier2014_3

Fluorescence images of anti-E.coli O157 antibody pattern before and after bacteria detection.

Nanotechnology applied to biomolecule interaction studies and micro/nano-environments for regenerative medicine applications

  • Design, production and characterization of micro/nanoenviroments with different biocompatible materials for cell behavior studies (adhesion, proliferation, differentiation)
  • Design, production and characterization of scaffolds with a topography and chemical composition controlled at the nanoscale for regenerative therapies based on stem cells
  • Biophysical description of cellular phenomena (cell migration, differentiation) using micro/nanotechnologies, cell biology tools and soft matter physics.
  • Magnetic nanoparticles-biomolecules interactions and their applications

Microfluidic systems for biological studies and Organ-on-Chip devices

  • Microfluidic chip for blood/plasma filtering
  • Spleen on a Chip development
  • Nanoporous based systems for kidney on chip developments.Engineering microfluidic platforms for neurobiological studies.
  • Engineering microfluidic platforms for neurobiological studies.
samitier2014_4

Sensor array for in vivo Ischemia detection

 

News/Jobs

Josep Samitier selected as Spanish expert in bio- and nanotechnology for OECD
29/05/14

IBEC Director Josep Samitier is one of the four delegates for Spain nominated to take part in the new Working Party on Biotechnology, Nanotechnology and Converging Technologies (BNCT) of the OECD, which will start work in January 2015.


Faster and more accurate testing for causes of lower respiratory tract infections
07/04/14

Research and industry collaboration develops miniature diagnostic platform for respiratory infections such as pneumonia and infectious bronchitis Featured on the cover of the latest issue of Lab on a Chip


“Crean en España el primer bazo dentro de un chip capaz de actuar como este órgano humano”
19/03/14

The recent press release about the design of the first-ever functional 3D splenon capable of reproducing the function of the spleen, which is to filter red blood cells, by researchers from IBEC and CRESIB received lots of media coverage. Below are just a few examples.


“Càpsules de Ciència: Josep Samitier”
07/01/14

IBEC Director Josep Samitier stars in one of the Associació per a la Divulgació de la Cultura Cientifica (ADICC)’s ‘Càpsules de Ciència’, a series of videos highlighting biomedical and biotechnology researchers in Catalonia. In the video, he explains nanobiotechnology with the submarine on Ronda de Dalt as a backdrop, which represents the way nanodevices can travel through our bodies much like tiny submarines on a rescue mission.


Researchers and clinicians create first functional human ‘splenon-on-a-chip’
07/03/14

Scientists from IBEC and ISGlobal’s research centre CRESIB have designed the first-ever functional 3D splenon capable of reproducing the function of the spleen, which is to filter red blood cells.


“Nanorobots de disseny per atacar la malària”
18/11/2013

IBEC Director and Head of Nanobioengineering, Josep Samitier, and the head of the joint IBEC/CRESIB unit on Nanomalaria, Xavier Fernández-Busquets, both featured in an article in the Catalan daily newspaper Ara this weekend.


“El hombre biónico ya no es una utopía”
15/10/2013

IBEC appears in an article about bionics and rebuilding the human body published in Argentine daily newspaper El Tribuno (Salta), when Josep Samitier is quoted as an expert opinion on the subject.


IBEC researcher in first class of d·HEALTH Barcelona
25/09/2013

IBEC senior researcher Mateu Pla is one of the first class of just 12 fellows chosen for the first Design Health Barcelona (d·HEALTH Barcelona) higher education programme, which starts this week.


“El futur augura que tindrem la salut a l’abast de la mà”
31/07/2013

An interview with IBEC director Josep Samitier features in the summer edition of Alma, the magazine of the Obra Social “La Caixa”.


“Herramientas para diseñar laboratorios que caben en un chip”
16/04/2013

In this week’s Diario Medico Special on Diagnostic Therapies, IBEC acting director Josep Samitier’s expert opinion is quoted in an article about lab-on-a-chip technologies.


A promising strategy to target malaria
06/12/2012

A paper by the Nanobioengineering group reveals a new strategy for targeted malaria treatment that doesn’t rely on the use of expensive antibodies.


New generation robots – inspired by plants
12/06/2012

Last week saw the start of the three-year European project PLANTOID, of which IBEC’s Nanobioengineering group is a partner, which aims to design and develop robots inspired by plants.


A journey through the technological revolution
27/04/2012

IBEC associate director Josep Samitier officially opened the Tecnorrevolución exhibition at Barcelona’s CosmoCaixa museum last night.


“Sin un andamio de apoyo”
11/04/2011

IBEC associate director Josep Samitier is an expert opinion quoted in El Periodico last week regarding a story about a Japanese study that succeeded in growing an embryonic eye from the stem cells of mice. He describes this first successful attempt to obtain a complex three-dimensional structure spontaneously as an important breakthrough, as it opens new avenues into coaxing the growth of cells using a method that the researchers describe as an ‘inside job’ rather than using a support structure as is usually the case.


3rd BOND Consortium Meeting at IBEC
14/03/2011

The members of the BOND consortium met at IBEC at the beginning of last week for the 3rd technical meeting of the EU-funded international project.


Better tools for food safety
09/02/2011

On 2 February the kick-off meeting of a transnational project coordinated by postdoc Beatriz Prieto of the Nanobioengineering group took place at IBEC. The project, ‘Development of innovative tools for Ochratoxin A’, will evaluate and tackle the threat to humans and animals of exposure to mycotoxins (fungal metabolites) in food.


Spanish Minister for Education visits Nanobioengineering group
09/02/2011

On a tour of the Parc Científic de Barcelona (PCB) earlier this week, the Minister for Education, Ángel Gabilondo, paid a visit to IBEC’s Nanobioengineering lab and spoke at length to Associate Director Josep Samitier about his group’s research.


E-News Biocat: “Nanomedicine: Where Nanotechnology, biotechnology and the health sciences come together”
20/01/2011

IBEC associate director Josep Samitier is a contributor to the January edition of Biocat’s e-newsletter.


El Pais: “Cuestión de límites”
05/10/2010

“A Question of Limits” – an article written by associate director Josep Samitier to accompany a feature by El Pais journalist Mónica López Ferrado, “Los ‘nanoriesgos’ no son tan diminutos” (“‘Nanorisks’ are not so small’).


IBEC lends nanotech expertise to national exhibition
01/10/2010

If you’ve ever wanted to move an object using the power of your mind, predict the spread of a virus and the development of a pandemic, or watch a mini robot travel through the body to deliver a drug, you need look no further than the new Tecnorevolució exhibition, which has been created with IBEC’s associate director Josep Samitier as scientific adviser.


Famous for five minutes: TV3
23/09/2010

IBEC Project manager Juan Fran Sangüesa made the news on 22 September when he was interviewed for the midday bulletin on TV3, the Catalan television channel.


El Periódico de Catalunya: “Estamos desarrollando una nariz bioelectrónica que será capaz de diagnosticar enfermedades”
15/03/2010

In an interview, Josep Samitier, IBEC’s associated director and group leader of Nanobioengineering research group, explains the scientific basis and the development of a bioelectronic device to detect diseases.


La Vanguardia Sunday debate section: “El reto de la nanotecnología – Aportación minúscula, mejora grande”
14/03/2010

Josep Samitier, IBEC’s associated director and group leader of Nanobioengineering research group, analyzes the challenges and contributions of nanotechnology.


Novel Evolutionary Theory for the Explosion of Life
15/10/2009

The Cambrian Explosion is widely regarded as one of the most relevant episodes in the history of life on Earth, when the vast majority of animal phyla first appear in the fossil record. However, the causes of its origin have been object of debate for decades and the question of what was the trigger for the single cell microorganisms Precambrian Age (500 Mio. Years ago) to assemble and organize into multicellular organisms (Metazoans) has remained unanswered until now.


Project Kick-off for a New Bioelectronic Nose
07/10/2009

Advances in odour sensing technologies and artificial intelligence have given impetus to the use of smell in various fields, such as food safety, disease diagnosis, security, and the environment. Current electronic noses, based on electronic sensors, have considerable limitations in terms of sensitivity, reliability, and selectivity.


The Guardian Supplement: Nanotechnology 2009 – Part 2
27/08/2009

“Ask the Experts”: In an interview, Josep Samitier, Associate Director of IBEC, talks about the potential, the impact and the contributions of nanobiotechnology.


Josep Samitier appointed Rector of the University of Barcelona
21/04/2008

Josep Samitier, head of the IBEC nanobioengineering group, was appointed Acting Rector of the University of Barcelona (UB) on 21 April.


La recerca al Laboratori de Nanobioenginyeria de l’IBEC a El Periódico
15/01/2008

La recerca al Laboratori de Nanobioenginyeria de l’IBEC a El Periódico El passat dilluns 14 de gener, el diari El Periódico de Catalunya, dins la secció de Societat i Ciència, destacava la actualitat i la rellevància de la recerca en cèl·lules mare per a aplicacions terapèutiques, i concretament la recerca que es porta a terme a l’IBEC, dins el grup de recerca de Micro/nanosistemes per aplicacions biomèdiques dirigit pel Prof. Josep Samitier.


The textbook Molecular Cell Biology selects a figure from a nanobioengineering researcher at IBEC
12/07/2007

The prestigious reference textbook Molecular Cell Biology (Lodish et al.) has selected for its 6th edition (2008) a figure from the researcher at the nanobioengineering laboratory at the IBEC, Dr. Xavier Fernández-Busquets. Thanks to this important recognition of scientific excellence, the IBEC is the only Spanish institution appearing in the acknowledgements of the textbook, out of a total of 150 universitites and research centres.

Projects

EU-funded projects
PLANTOID: Innovative Robotic Artefacts Inspired by Plant Roots for Soil Monitoring ICT Josep Samitier
National projects
Universal diagnostic platforms based on oligonucleotide cofidied nanoparticles and DNA microarray sensor devices I+D-Investigación fundamental no orientada Josep Samitier

Publications

Estévez, M., Martínez, E., Yarwood, S. J., Dalby, M. J., Samitier, J., (2015). Adhesion and migration of cells responding to microtopography Journal of Biomedical Materials Research - Part A 1035, 1659-1668

del Moral-Zamora, Beatriz, Punter-Villagrassa, Jaime, Oliva-Brañas, Ana M., Álvarez-Azpeitia, Juan Manuel, Colomer-Farrarons, Jordi, Samitier, Josep, Homs-Corbera, Antoni, Miribel-Català, Pere Ll, (2015). Combined dielectrophoretic and impedance system for on-chip controlled bacteria concentration: application to Escherichia coli Electrophoresis , n/a-n/a

Del Moral Zamora, B., Álvarez Azpeitia, J.M., Oliva Brañas, A.M., Colomer-Farrarons, J., Castellarnau, M., Miribel-Català, P., Homs-Corbera, A., Juárez, A., Samitier, J., (2015). Continuous flow dielectrophoretic concentrator enhancement based on dielectric poles Electrophoresis ,

del Moral Zamora, Beatriz, Manuel Álvarez Azpeitia, Juan, Brañas, Ana Ma Oliva, Colomer-Farrarons, Jordi, Castellarnau, Marc, Miribel-Català, Pere Ll, Homs-Corbera, Antoni, Juárez, Antonio, Samitier, Josep, (2015). Dielectrophoretic concentrator enhancement based on dielectric poles for continuously flowing samples Electrophoresis , n/a-n/a

Rigat-Brugarolas, L. G., Homs-Corbera, A., Samitier, J., (2015). Highly hydrophilic microfluidic device prototyping using a novel poly(dimethylsiloxane)-based polymeric mix RSC Advances The Royal Society of Chemistry 510, 7423-7425

Barreiros dos Santos, M., Azevedo, S., Agusil, J. P., Prieto-Simón, B., Sporer, C., Torrents, E., Juárez, A., Teixeira, V., Samitier, J., (2015). Label-free ITO-based immunosensor for the detection of very low concentrations of pathogenic bacteria Bioelectrochemistry 101, 146-152

Caballero, D., Samitier, J., (2014). Different strategies for the fabrication of cell culture chambers for live-cell imaging studies Chips and Tips 1412, 1-5

Caballero, D., Samitier, J., (2014). Different strategies for the fabrication of cell culture chambers for live-cell imaging studies Chips and Tips 0809, 1-4

Rigat-Brugarolas, L. G., Homs, A., Samitier, J., (2014). Reservoir poly(dimethylsiloxane) cap fabrication Chips and Tips 1410, 1-4

Rigat-Brugarolas, L. G., Homs, A., Samitier, J., (2014). Simple alignment marks patterning for multilayered master fabrication Chips and Tips 143, 1-7

Rigat-Brugarolas, L. G., Homs, A., Samitier, J., (2014). Simple fabrication of three-dimensional ramped microstructures using SU-8 negative photoresist Chips and Tips 143, 1-5

Oliva, A. M., Homs-Corbera, A., Torrents, E., Juarez, A., Samitier, J., (2014). Synergystic effect of temperature and electric field intensity in Escherichia coli inactivation Micro and Nanosystems 62, 79-86

del Moral Zamora, B., Azpeitia, J. M. Á, Farrarons, J. C., Català, P. L. M., Corbera, A. H., Juárez, A., Samitier, J., (2014). Towards point-of-use dielectrophoretic methods: A new portable multiphase generator for bacteria concentration Micro and Nanosystems 62, 71-78

Lagunas, A., Castaño, A. G., Artés, J. M., Vida, Y., Collado, D., Pérez-Inestrosa, E., Gorostiza, P., Claros, S., Andrades, J. A., Samitier, J., (2014). Large-scale dendrimer-based uneven nanopatterns for the study of local arginine-glycine-aspartic acid (RGD) density effects on cell adhesion Nano Research 73, 399-409

Tahirbegi, I. B., Mir, M., Schostek, S., Schurr, M., Samitier, J., (2014). In vivo ischemia monitoring array for endoscopic surgery Biosensors and Bioelectronics 61, 124-130

Prieto-Simón, B., Samitier, J., (2014). "signal off" aptasensor based on enzyme inhibition induced by conformational switch Analytical Chemistry 863, 1437-1444

Rigat-Brugarolas, L. G., Elizalde-Torrent, A., Bernabeu, M., De Niz, M., Martin-Jaular, L., Fernandez-Becerra, C., Homs-Corbera, A., Samitier, J., Del Portillo, H. A., (2014). A functional microengineered model of the human splenon-on-a-chip Lab on a Chip 1410, 1715-1724

Van Heirstraeten, L., Spang, P., Schwind, C., Drese, K. S., Ritzi-Lehnert, M., Nieto, B., Camps, M., Landgraf, B., Guasch, F., Corbera, A. H., Samitier, J., Goossens, H., Malhotra-Kumar, S., Roeser, T., (2014). Integrated DNA and RNA extraction and purification on an automated microfluidic cassette from bacterial and viral pathogens causing community-acquired lower respiratory tract infections Lab on a Chip 149, 1519-1526

Comelles, J., Caballero, D., Voituriez, ., Hortigüelaa, V., Wollrab, V., Godeau, A. L., Samitier, J., Martínez, E., Riveline, D., (2014). Cells as active particles in asymmetric potentials: Motility under external gradients Biophysical Journal 1077, 1513-1522

Zaffino, R. L., Mir, M., Samitier, J., (2014). Label-free detection of DNA hybridization and single point mutations in a nano-gap biosensor Nanotechnology 2510, 105501 (8)

González, L., Otero, J., Agusil, J. P., Samitier, J., Adan, J., Mitjans, F., Puig-Vidal, M., (2014). Micropattern of antibodies imaged by shear force microscopy: Comparison between classical and jumping modes Ultramicroscopy 136, 176-184

Castillo-Fernandez, O., Rodriguez-Trujillo, R., Gomila, G., Samitier, J., (2014). High-speed counting and sizing of cells in an impedance flow microcytometer with compact electronic instrumentation Microfluidics and Nanofluidics 161-2, 91-99

Juanola-Feliu, E., Miribel-Català, P. L., Avilés, C. P., Colomer-Farrarons, J., González-Piñero, M., Samitier, J., (2014). Design of a customized multipurpose nano-enabled implantable system for in-vivo theranostics Sensors 1410, 19275-19306

Mir, M., Lugo, R., Tahirbegi, I. B., Samitier, J., (2014). Miniaturizable ion-selective arrays based on highly stable polymer membranes for biomedical applications Sensors 147, 11844-11854

Tahirbegi, I. B., Alvira, M., Mir, M., Samitier, J., (2014). Simple and fast method for fabrication of endoscopic implantable sensor arrays Sensors 147, 11416-11426

Oliva, A. M., Homs, A., Torrents, E., Juarez, A., Samitier, J., (2014). Effect of electric field and temperature in E.Coli viability IFMBE Proceedings Springer 41, 1833-1836

Rigat-Brugarolas, L. G., Bernabeu, M., Elizalde, A., de Niz, M., Martin-Jaular, L., Fernandez-Becerra, C., Homs-Corbera, A., del Portillo, H. A., Samitier, J., (2014). Human splenon-on-a-chip: Design and validation of a microfluidic model resembling the interstitial slits and the close/fast and open/slow microcirculations IFMBE Proceedings Springer 41, 884-887

Juanola-Feliu, Esteve, Colomer-Farrarons, Jordi, Miribel-Català, Pere, González-Piñero, Manel, Samitier, Josep, (2014). Nano-enabled implantable device for glucose monitoring Wiley-VCH Verlag GmbH & Co. KGaA , 247-263

del Moral Zamora, B., Azpeitia, J. M. Á, Farrarons, J. C., Català, P. L. M., Corbera, A. H., Juárez, A., Samitier, J., (2014). Towards point-of-use dielectrophoretic methods: A new portable multiphase generator for bacteria concentration IFMBE Proceedings Springer International Publishing 41, 856-859

Barreiros dos Santos, M., Agusil, J. P., Prieto-Simón, B., Sporer, C., Teixeira, V., Samitier, J., (2013). Highly sensitive detection of pathogen Escherichia coli O157: H7 by electrochemical impedance spectroscopy Biosensors and Bioelectronics 451, 174-180

Tahirbegi, Islam Bogachan, Mir, Monica, Samitier, Josep, (2013). Real-time monitoring of ischemia inside stomach Biosensors and Bioelectronics 401, 323-328

Lagunas, A., Comelles, J., Oberhansl, S., Hortigüela, V., Martínez, E., Samitier, J., (2013). Continuous bone morphogenetic protein-2 gradients for concentration effect studies on C2C12 osteogenic fate Nanomedicine: Nanotechnology, Biology, and Medicine 95, 694-701

Novo, S., Penon, O., Barrios, L., Nogués, C., Santaló, J., Durán, S., Gómez-Matínez, R., Samitier, J., Plaza, J. A., Pérez-García, L., Ibáñez, E., (2013). Direct embryo tagging and identification system by attachment of biofunctionalized polysilicon barcodes to the zona pellucida of mouse embryos Human Reproduction 286, 1519-1527

Caballero, D., Fumagalli, L., Teixidor, F., Samitier, J., Errachid, A., (2013). Directing polypyrrole growth by chemical micropatterns: A study of high-throughput well-ordered arrays of conductive 3D microrings Sensors and Actuators B: Chemical 177, 1003-1009

Prats-Alfonso, E., Oberhansl, S., Lagunas, A., Martínez, E., Samitier, J., Albericio, F., (2013). Effective and versatile strategy for the total solid-phase synthesis of alkanethiols for biological applications European Journal of Organic Chemistry 20137, 1233-1239

Rodriguez-Segui, Santiago A., Ortuno, Maria Jose, Ventura, Francesc, Martinez, Elena, Samitier, Josep, (2013). Simplified microenvironments and reduced cell culture size influence the cell differentiation outcome in cellular microarrays Journal of Materials Science: Materials in Medicine 241, 189-198

Diéguez, Lorena, Caballero, David, Calderer, Josep, Moreno, Mauricio, Martínez, Elena, Samitier, Josep, (2012). Optical gratings coated with thin Si3N4 layer for efficient immunosensing by optical waveguide lightmode spectroscopy Biosensors 22, 114-126

Oberhansl, Sabine, Hirtz, Michael, Lagunas, Anna, Eritja, Ramon, Martinez, Elena, Fuchs, Harald, Samitier, Josep, (2012). Facile modification of silica substrates provides a platform for direct-writing surface click chemistry Small 84, 541-545

Lagunas, Anna , Comelles, Jordi, Martínez, Elena, Prats-Alfonso, Elisabet , Acosta, Gerardo A., Albericio, Fernando , Samitier, Josep , (2012). Cell adhesion and focal contact formation on linear RGD molecular gradients: study of non-linear concentration dependence effects Nanomedicine: Nanotechnology, Biology and Medicine 84, 432-439

Mir, Mònica , Tahirbegi, Islam Bogachan , Valle-Delgado, Juan José , Fernàndez-Busquets, Xavier , Samitier, Josep , (2012). In vitro study of magnetite-amyloid Nanomedicine: Nanotechnology, Biology and Medicine 86, 974-980

Esquivel, Juan Pablo , Castellarnau, Marc , Senn, Tobias , Löchel, Bernd , Samitier, Josep , Sabaté, Neus , (2012). Fuel cell-powered microfluidic platform for lab-on-a-chip applications Lab on a Chip 121, 74-79

Esquivel, J. P., Colomer-Farrarons, J., Castellarnau, M., Salleras, M., del Campo, F. J., Samitier, J., Miribel-Catala, P., Sabate, N., (2012). Fuel cell-powered microfluidic platform for lab-on-a-chip applications: Integration into an autonomous amperometric sensing device Lab on a Chip 1221, 4232-4235

Parra-Cabrera, C., Sporer, C., Rodriguez-Villareal, I., Rodriguez-Trujillo, R., Homs-Corbera, A., Samitier, J., (2012). Selective in situ functionalization of biosensors on LOC devices using laminar co-flow Lab on a Chip 1220, 4143-4150

Yang, Cheng, Lates, Vasilica, Prieto-Simón, Beatriz, Marty, Jean-Louis, Yang, Xiurong, (2012). Aptamer-DNAzyme hairpins for biosensing of Ochratoxin A Biosensors and Bioelectronics 321, 208-212

Penon, O., Novo, S., Duran, S., Ibanez, E., Nogues, C., Samitier, J., Duch, M., Plaza, J. A., Perez-Garcia, L., (2012). Efficient biofunctionalization of polysilicon barcodes for adhesion to the zona pellucida of mouse embryos Bioconjugate Chemistry 2312, 2392-2402

Tort, N., Salvador, J. P., Avino, A., Eritja, R., Comelles, J., Martinez, E., Samitier, J., Marco, M. P., (2012). Synthesis of steroid-oligonucleotide conjugates for a DNA site-encoded SPR immunosensor Bioconjugate Chemistry 2311, 2183-2191

Caballero, D., Martinez, E., Bausells, J., Errachid, A., Samitier, J., (2012). Impedimetric immunosensor for human serum albumin detection on a direct aldehyde-functionalized silicon nitride surface Analytica Chimica Acta 720, 43-48

Comelles, J., Hortiguela, V., Samitier, J., Martinez, E., (2012). Versatile gradients of covalently bound proteins on microstructured substrates Langmuir 2838, 13688-13697

Campas, Monica, Garibo, Diana, Prieto-Simon, Beatriz, (2012). Novel nanobiotechnological concepts in electrochemical biosensors for the analysis of toxins Analyst 1375, 1055-1067

Calò, A., Sanmartí-Espinal, M., Iavicoli, P., Persuy, M. A., Pajot-Augy, E., Gomila, G., Samitier, J., (2012). Diffusion-controlled deposition of natural nanovesicles containing G-protein coupled receptors for biosensing platforms Soft Matter 846, 11632-11643

Valle-Delgado, J. J., Liepina, I., Lapidus, D., Sabaté, R., Ventura, S., Samitier, J., Fernàndez-Busquets, X., (2012). Self-assembly of human amylin-derived peptides studied by atomic force microscopy and single molecule force spectroscopy Soft Matter 84, 1234-1242

Villar-Pique, A., De Groot, N. S., Sabaté, R., Acebrón, S. P., Celaya, G., Fernández-Busquets, X., Muga, A., Ventura, S., (2012). The effect of amyloidogenic peptides on bacterial aging correlates with their intrinsic aggregation propensity Journal of Molecular Biology 4212-3, 270-281

Urban, P., Valle-Delgado, J. J., Moles, E., Marques, J., Diez, C., Fernandez-Busquets, X., (2012). Nanotools for the delivery of antimicrobial peptides Current Drug Targets 139, 1158-1172

Baccar, Z.M., Caballero, D., Eritja, R., Errachid, A., (2012). Development of an impedimetric DNA-biosensor based on layered double hydroxide for the detection of long ssDNA sequences Electrochimica Acta 74, 123-129

Kuphal, M., Mills, C.A., Korri-Youssoufi, H., Samitier, J., (2012). Polymer-based technology platform for robust electrochemical sensing using gold microelectrodes Sensors and Actuators B: Chemical 1611, 279-284

Rosa Hernández, M., Urbán, P., Casals, E., Estelrich, J., Escolar, G., Galán, A. M., (2012). Liposomes bearing fibrinogen could potentially interfere with platelet interaction and procoagulant activity International Journal of Nanomedicine 7, 2339-2347

Juanola-Feliu, E., Colomer-Farrarons, J., Miribel-Català , P., Samitier, J., Valls-Pasola, J., (2012). Market challenges facing academic research in commercializing nano-enabled implantable devices for in-vivo biomedical analysis Technovation 323-4, 193-204

Veeregowda, D. H., van der Mei, H. C., de Vries, J., Rutland, M. W., Valle-Delgado, J. J., Sharma, P. K., Busscher, H. J., (2012). Boundary lubrication by brushed salivary conditioning films and their degree of glycosylation Clinical Oral Investigations 165, 1499-1506

Gallach, D., Torres-Costa, V., García-Pelayo, L., Climent-Font, A., Martín-Palma, R. J., Barreiros-Das-Santos, M., Sporer, C., Samitier, J., Manso, M., (2012). Properties of bilayer contacts to porous silicon Applied Physics A: Materials Science and Processing 1072, 293-300

Azevedo, S., Diéguez, L., Carvalho, P., Carneiro, J. O., Teixeira, V., Martínez, E., Samitier, J., (2012). Deposition of ITO thin films onto PMMA substrates for waveguide based biosensing devices Journal of Nano Research 17, 75-83

Colomer-Farrarons, J., Miribel-Català , P., Juanola-Feliu, E., Samitier, J., (2012). A proof-of-concept of a multi-harvesting power source in a low-voltage CMOS technology IEEE Computer Society IEEE , 655-659

Valle-Delgado, J. J., Molina-Bolívar, J. A., Galisteo-González, F., Gálvez-Ruiz, M. J., (2011). Evidence of hydration forces between proteins Current Opinion in Colloid and Interface Science 166, 572-578

Urban, Patricia, Estelrich, Joan, Cortés, Alfred, Fernàndez-Busquets, Xavier, (2011). A nanovector with complete discrimination for targeted delivery to Plasmodium falciparum-infected versus non-infected red blood cells in vitro Journal of Controlled Release 1512, 202-211

Ivon Rodriguez-Villarreal, Angeles, Tarn, Mark D., Madden, Leigh A., Lutz, Julia B., Greenman, John, Samitier, Josep, Pamme, Nicole, (2011). Flow focussing of particles and cells based on their intrinsic properties using a simple diamagnetic repulsion setup Lab on a Chip 117, 1240-1248

Sánchez-Martín, M. J., Urbán, P., Pujol, M., Haro, I., Alsina, M. A., Busquets, M. A., (2011). Biophysical investigations of GBV-C E1 peptides as potential inhibitors of HIV-1 fusion peptide ChemPhysChem 1215, 2816-2822

Castillo-Fernandez, Oscar, Salieb-Beugelaar, Georgette B., van Nieuwkasteele, Jan W., Bomer, Johan G., Arundell, Martin, Samitier, Josep, van den Berg, Albert, Eijkel, Jan C. T., (2011). Electrokinetic DNA transport in 20 nm-high nanoslits: Evidence for movement through a wall-adsorbed polymer nanogel Electrophoresis 3218, 2402-2409

Mir, Monica, Martinez-Rodriguez, Sergio, Castillo-Fernandez, Oscar, Homs-Corbera, Antoni, Samitier, Josep, (2011). Electrokinetic techniques applied to electrochemical DNA biosensors Electrophoresis 328, 811-821

Urban, Patricia, Estelrich, Joan, Adeva, Alberto, Cortes, Alfred, Fernandez-Busquets, Xavier, (2011). Study of the efficacy of antimalarial drugs delivered inside targeted immunoliposomal nanovectors Nanoscale Research Letters 61, 620

Barthelmebs, L., Jonca, J., Hayat, A., Prieto-Simon, B., Marty, J. L., (2011). Enzyme-Linked Aptamer Assays (ELAAs), based on a competition format for a rapid and sensitive detection of Ochratoxin A in wine Food Control 225, 737-743

Rodriguez-Segui, Santiago A., Pons Ximenez, Jose Ignacio, Sevilla, Lidia, Ruiz, Ana, Colpo, Pascal, Rossi, Francois, Martinez, Elena, Samitier, Josep, (2011). Quantification of protein immobilization on substrates for cellular microarray applications Journal of Biomedical Materials Research - Part A 98A2, 245-256

Fernandez, Javier G., Samitier, Josep, Mills, Christopher A., (2011). Simultaneous biochemical and topographical patterning on curved surfaces using biocompatible sacrificial molds Journal of Biomedical Materials Research - Part A 98A2, 229-234

Tahirbegi, I. B., Mir, M., (2011). Slit-wave model for band structures in solid state physics Modern Physics Letters B 253, 151-161

Juanola-Feliu, E., Colomer-Farrarons, J., Miribel-Catala, P., Samitier, J., Valls-Pasola, J., (2011). Challenges facing academic research in commercializing event-detector implantable devices for an in-vivo biomedical subcutaneous device for biomedical analysis Proceedings of the SPIE - The International Society for Optical Engineering SPIE - The International Society for Optical Engineering, USA 8067, 80670P

del Moral Zamora, B., Colomer, J., Mir, M., Homs, A., Miribel, P., Samitier, J., (2011). Combined impedance and dielectrophoresis portable device for point-of-care analysis Proceedings SPIE SPIE 8068, 80680T (19)

Punter-Villagrasa, J., Colomer-Farrarons, J., Miribel-Catala, P., Puig-Vidal, M., Samitier, J., (2011). Discrete to full custom ASIC solutions for bioelectronic applications Proceedings of the SPIE - The International Society for Optical Engineering SPIE - The International Society for Optical Engineering 8067, 80670Q

Colomer-Farrarons, Jordi , Miribel-Català, Pedro Luís, Samitier, Josep , (2011). Low-voltage µpower CMOS subcutaneous biomedical implantable device for true/false applications Biomedical Engineering ACTA Press Biomedical Engineering, 424-428

Mir, M., (2011). Aptamers: The new biorecognition element for proteomic biosensing Nova Science Publishers, Inc , -----

Colomer-Farrarons, Jordi, Miribel-Català, Pere LI., Rodríguez-Villarreal, A. Ivón, Samitier, Josep, (2011). Portable bio-devices: Design of electrochemical instruments from miniaturized to implantable devices InTech Biomedical Engineering, 373-400

Martinez, Elena, Samitier, Josep, (2011). Soft lithography and variants Wiley-VCH Verlag GmbH&Co , 57-66

Prieto-Simón, B., Campà s, M., Marty, J. L., (2010). Electrochemical aptamer-based sensors Bioanalytical Reviews 12, 141-157

Valle-Delgado, J. J., Alfonso-Prieto, M., de Groot, N. S., Ventura, S., Samitier, J., Rovira, C., Fernandez-Busquets, X., (2010). Modulation of A beta(42) fibrillogenesis by glycosaminoglycan structure FASEB Journal 2411, 4250-4261

Sisquella, X., de Pourcq, K., Alguacil, J., Robles, J., Sanz, F., Anselmetti, D., Imperial, S., Fernandez-Busquets, X., (2010). A single-molecule force spectroscopy nanosensor for the identification of new antibiotics and antimalarials FASEB Journal 2411, 4203-4217

Rodriguez-Villarreal, A. I., Arundell, M., Carmona, M., Samitier, J., (2010). High flow rate microfluidic device for blood plasma separation using a range of temperatures Lab on a Chip 102, 211-219

Valente, T., Gella, A., Fernandez-Busquets, X., Unzeta, M., Durany, N., (2010). Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus Neurobiology of Disease 371, 67-76

Fernandez-Busquets, X., Ponce, J., Bravo, R., Arimon, M., Martianez, T., Gella, A., Cladera, J., Durany, N., (2010). Modulation of amyloid beta peptide(1-42) cytotoxicity and aggregation in vitro by glucose and chondroitin sulfate Current Alzheimer Research 75, 428-438

Comelles, J., Estevez, M., Martinez, E., Samitier, J., (2010). The role of surface energy of technical polymers in serum protein adsorption and MG-63 cells adhesion Nanomedicine: Nanotechnology Biology and Medicine 61, 44-51

Estevez, M., Fernandez-Ulibarri, I., Martinez, E., Egea, G., Samitier, J., (2010). Changes in the internal organization of the cell by microstructured substrates Soft Matter 63, 582-590

Lagunas, A., Comelles, J., Martinez, E., Samitier, J., (2010). Universal chemical gradient platforms using poly(methyl methacrylate) based on the biotin streptavidin interaction for biological applications Langmuir 2617, 14154-14161

Gallego, I., Oncins, G., Sisquella, X., Fernandez-Busquets, X., Daban, J. R., (2010). Nanotribology results show that DNA forms a mechanically resistant 2D network in metaphase chromatin plates Biophysical Journal 9912, 3951-3958

Harder, A., Walhorn, V., Dierks, T., Fernandez-Busquets, X., Anselmetti, D., (2010). Single-molecule force spectroscopy of cartilage aggrecan self-adhesion Biophysical Journal 9910, 3498-3504

Sabaté, R., Espargaró, A., de Groot, N. S., Valle-Delgado, J. J., Fernàndez-Busquets, X., Ventura, S., (2010). The role of protein sequence and amino acid composition in amyloid formation: Scrambling and backward reading of IAPP amyloid fibrils Journal of Molecular Biology 4042, 337-352

Darwish, N., Caballero, D., Moreno, M., Errachid, A., Samitier, J., (2010). Multi-analytic grating coupler biosensor for differential binding analysis Sensors and Actuators B: Chemical 1442, 413-417

de Oliveira, I. A. M., Vocanson, F., Uttaro, J. P., Asfari, Z., Mills, C. A., Samitier, J., Errachid, A., (2010). Characterization of a self-assembled monolayer based on a calix[4]crown-5 derivate: fabrication of a chemical sensor sensitive to calcium Journal of Nanoscience and Nanotechnology 101, 413-420

Caballero, D., Villanueva, G., Plaza, J. A., Mills, C. A., Samitier, J., Errachid, A., (2010). Sharp high-aspect-ratio AFM tips fabricated by a combination of deep reactive ion etching and focused ion beam techniques Journal of Nanoscience and Nanotechnology 101, 497-501

Sanmarti, M., Iavicoli, P., Pajot-Augy, E., Gomila, G., Samitier, J., (2010). Human olfactory receptors immobilization on a mixed self assembled monolayer for the development of a bioelectronic nose Procedia Engineering (EUROSENSOR XXIV CONFERENCE) Elsevier Science 5, 786-789

Illa, X., Rodriguez-Trujillo, R., Ordeig, O., De Malsche, W., Homs-Corbera, A., Gardeniers, H., Desmet, G., Kutter, J. P., Samitier, J., Romano-Rodríguez, A., (2010). Simultaneous impedance and fluorescence detection of proteins in a cyclo olefin polymer chip containing a column with an ordered pillar array with integrated gold microelectrodes MicroTAS 2010 UoG 2, 1280-1282

Fernàndez-Busquets, X., Körnig, A., Bucior, I., Burger, M. M., Anselmetti, D., (2009). Self-recognition and Ca2+-dependent carbohydrate-carbohydrate cell adhesion provide clues to the cambrian explosion Molecular Biology and Evolution 2611, 2551-2561

Guix, F. X., Ill-Raga, G., Bravo, R., Nakaya, T., de Fabritiis, G., Coma, M., Miscione, G. P., Villa-Freixa, J., Suzuki, T., Fernandez-Busquets, X., Valverde, M. A., de Strooper, B., Munoz, F. J., (2009). Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation Brain 1325, 1335-1345

Fernandez, J. G., Mills, C. A., Samitier, J., (2009). Complex microstructured 3D surfaces using chitosan biopolymer Small 55, 614-620

Caballero, D., Samitier, J., Bausells, J., Errachid, A., (2009). Direct patterning of anti-human serum albumin antibodies on aldehyde-terminated silicon nitride surfaces for HSA protein detection Small 513, 1531-1534

Pla, D., Sischka, A., Albericio, F., Alvarez, M., Fernandez-Busquets, X., Anselmetti, D., (2009). Optical-tweezers study of topoisomerase inhibition Small 511, 1269-1272

Hosta, L., Pla-Roca, M., Arbiol, J., Lopez-Iglesias, C., Samitier, J., Cruz, L. J., Kogan, M. J., Albericio, F., (2009). Conjugation of Kahalalide F with gold nanoparticles to enhance in vitro antitumoral activity Bioconjugate Chemistry 201, 138-146

Mir, M., Cameron, P. J., Zhong, X., Azzaroni, O., Alvarez, M., Knoll, W., (2009). Anti-fouling characteristics of surface-confined oligonucleotide strands bioconjugated on streptavidin platforms in the presence of nanomaterials Talanta 783, 1102-6

Mir, M., Homs, A., Samitier, J., (2009). Integrated electrochemical DNA biosensors for lab-on-a-chip devices Electrophoresis 3019, 3386-3397

Gimenez-Oya, V., Villacanas, O., Fernandez-Busquets, X., Rubio-Martinez, J., Imperial, S., (2009). Mimicking direct protein-protein and solvent-mediated interactions in the CDP-methylerythritol kinase homodimer: a pharmacophore-directed virtual screening approach Journal of Molecular Modeling 158, 997-1007

Lopez-Martinez, M. J., Campo, E. M., Caballero, D., Fernandez, E., Errachid, A., Esteve, J., Plaza, J. A., (2009). Versatile micropipette technology based on deep reactive ion etching and anodic bonding for biological applications Journal of Micromechanics and Microengineering 1910, 105013 (10 pp.)

Rodriguez-Segui, S. A., Pla-Roca, M., Engel, E., Planell, J. A., Martinez, E., Samitier, J., (2009). Influence of fabrication parameters in cellular microarrays for stem cell studies Journal of Materials Science: Materials in Medicine 207, 1525-1533

Caballero, D., Samitier, J., Errachid, A., (2009). Submerged nanocontact printing (SnCP) of thiols Journal of Nanoscience and Nanotechnology 911, 6478-6482

Engel, E., Martinez, E., Mills, C. A., Funes, M., Planell, J. A., Samitier, J., (2009). Mesenchymal stem cell differentiation on microstructured poly (methyl methacrylate) substrates Annals of Anatomy-Anatomischer Anzeiger 1911, 136-144

Gustavsson, J., Zine, N., Vocanson, F., Engel, E., Planell, J., Bausells, J., Samitier, J., Errachid, A., (2009). Characterization of potassium-selective field effect transistors based on 1,3-(di-4-oxabutanol)-calix[4]arene-crown-5 as ionophore Sensor Letters 75, 795-800

Colomer-Farrarons, J., Miribel-Catala , P., Saiz-Vela, A., Samitier, J., (2009). A 60 uW low-power low-voltage power management unit for a self-powered system based on low-cost piezoelectric powering generators Proceedings of the 35th European Solid-State Circuits Conference. ESSCIRC 2009 IEEE , 280-283

Colomer-Farrarons, J., Miribel-Catala , P., Rodriguez, I., Samitier, J., (2009). CMOS front-end architecture for in-vivo biomedical implantable devices 35th Annual Conference of IEEE Industrial Electronics (IECON 2009) IEEE , 4401-4408

Barreiros dos Santos, M., Sporer, C., Sanvicens, N., Pascual, N., Errachid, A., Martinez, E., Marco, M. P., Teixeira, V., Samiter, J., (2009). Detection of pathogenic Bacteria by Electrochemical Impedance Spectroscopy: Influence of the immobilization strategies on the sensor performance Procedia Chemistry Elsevier Science, BV 1, 1291-1294

Colomer, J., Miribel-Catala , P., Saiz-Vela, A., Rodriguez, I., Samitier, J., (2009). A low power CMOS biopotentiostat in a low-voltage 0.13 um digital technology 52nd IEEE International Midwest Symposium on Circuits and Systems (MWSCAS) IEEE , 172-175

Rodriguez-Segui, S. A., Bucior, I., Burger, M. M., Errachid, A., Fernandez-Busquets, X., (2009). Application of the quartz crystal microbalance to the study of multivalent carbohydrate-carbohydrate adhesion Sensor Letters AMER SCIENTIFIC PUBLISHERS 75, 782-787

Zazoua, A., Kherrat, R., Caballero, D., Errachid, A., Jaffrezic-Renault, N., Bessueille, F., Leonard, D., (2009). Characterisation of a Cr(VI) sensitive polysiloxane membrane by x-ray photoelectron spectrometry and atomic force microscopy Sensor Letters AMER SCIENTIFIC PUBLISHERS 75, 995-1000

Baccar, Z. M., Caballero, D., Zine, N., Jaffrezic-Renault, N., Errachid, A., (2009). Development of urease/layered double hydroxides nanohybrid materials for the urea detection: Synthesis, analytical and catalytic characterizations Sensor Letters AMER SCIENTIFIC PUBLISHERS 75, 676-682

Diaguez, L., Darwish, N., Mir, M., Martinez, E., Moreno, M., Samitier, J., (2009). Effect of the refractive index of buffer solutions in evanescent optical biosensors Sensor Letters AMER SCIENTIFIC PUBLISHERS 75, 851-855

Guaus, E., Torrent-Burgues, J., Zine, N., Errachid, A., (2009). Glassy carbon electrode modified with a langmuir-blodgett film of a thiomacrocyclic ionophore for Cu(II) recognition Sensor Letters AMER SCIENTIFIC PUBLISHERS 75, 1006-1011

Sporer, C., Casal, L., Caballero, D., Samitier, J., Errachid, A., Perez-Garcia, L., (2009). Novel anionophores for biosensor applications: nano characterisation of SAMS based on amphiphilic imidazolium protophanes and cyclophanes on gold surfaces Sensor Letters AMER SCIENTIFIC PUBLISHERS 75, 757-764

Baccar, Z. M., Hidouri, S., El Bari, N., Jaffrezic-Renault, N., Errachid, A., Zine, N., (2009). Stable immobilization of anti-beta casein antibody onto layered double hydroxides materials for biosensor applications Sensor Letters AMER SCIENTIFIC PUBLISHERS 75, 647-655

Zazoua, A., Morakchi, K., Kherrat, R., Samar, M. H., Errachid, A., Jaffrezic-Renault, N., Boubellout, R., (2008). Electrochemical characterization of an EIS sensor functionalized with a TOPO doped polymeric layer for Cr(VI) detection IRBM 292-3, 187-191

Bravo, R., Arimon, M., Valle-Delgado, J. J., Garcia, R., Durany, N., Castel, S., Cruz, M., Ventura, S., Fernandez-Busquets, X., (2008). Sulfated polysaccharides promote the assembly of amyloid beta(1-42) peptide into stable fibrils of reduced cytotoxicity Journal of Biological Chemistry 28347, 32471-32483

Morell, M., Bravo, R., Espargaro, A., Sisquella, X., Aviles, F. X., Fernandez-Busquets, X., Ventura, S., (2008). Inclusion bodies: Specificity in their aggregation process and amyloid-like structure Biochimica et Biophysica Acta - Molecular Cell Research 178310, 1815-1825

Embrechts, A., Feng, C. L., Mills, C. A., Lee, M., Bredebusch, I., Schnekenburger, J., Domschke, W., Vancso, G. J., Schönherr, H., (2008). Inverted microcontact printing on polystyrene-block-poly(tert-butyl acrylate) films: A versatile approach to fabricate structured biointerfaces across the length scales Langmuir 2416, 8841-8849

Issle, J., Pla-Roca, M., Martínez, E., Hartmann, U., (2008). Patterning of magnetic nanobeads on surfaces by poly(dimethylsiloxane) stamps Langmuir 243, 888-893

de Oliveira, I. A. M., Risco, D., Vocanson, F., Crespo, E., Teixidor, F., Zine, N., Bausells, J., Samitier, J., Errachid, A., (2008). Sodium ion sensitive microelectrode based on a p-tert-butylcalix[4]arene ethyl ester Sensors and Actuators B: Chemical 1301, 295-299

Fernandez, J. G., Mills, C. A., Martinez, E., Lopez-Bosque, M. J., Sisquella, X., Errachid, A., Samitier, J., (2008). Micro- and nanostructuring of freestanding, biodegradable, thin sheets of chitosan via soft lithography Journal of Biomedical Materials Research - Part A 85A1, 242-247

Guaus, E., Errachid, A., Torrent-Burgues, J., (2008). Voltammetric response of a glassy carbon electrode modified by a Langmuir-Blodgett film of a thiomacrocyclic compound Journal of Electroanalytical Chemistry 6141-2, 73-82

Lopez, M. J., Caballero, D., Campo, E. M., Perez-Castillejos, R., Errachid, A., Esteve, J., Plaza, J. A., (2008). Focused ion beam-assisted technology in sub-picolitre micro-dispenser fabrication Journal of Micromechanics and Microengineering 187, 8

Cho, S., Castellarnau, M., Samitier, J., Thielecke, H., (2008). Dependence of impedance of embedded single cells on cellular behaviour Sensors 82, 1198-1211

Martinez, E., Engel, E., Lopez-Iglesias, C., Mills, C. A., Planell, J. A., Samitier, J., (2008). Focused ion beam/scanning electron microscopy characterization of cell behavior on polymer micro-/nanopatterned substrates: A study of cell-substrate interactions Micron 392, 111-116

Mills, C. A., Fernandez, J. G., Errachid, A., Samitier, J., (2008). The use of high glass temperature polymers in the production of transparent, structured surfaces using nanoimprint lithography Microelectronic Engineering 859, 1897-1901

Renault, N. J., Korri-Youssoufi, H., Kyselovik, J., Auger, V., Errachid, A., Mills, C. A., Strohhöfer, C., Ali, Z., (2008). Impedimetric microanalysis system for deep vein thrombosis point-of-care testing EMBS'08 - "Personalized Healthcare through Technology" IEEE , 1856

Zazoua, A., Kherrat, R., Samar, M. H., Errachid, A., Jaffrezic-Renault, N., Bessueille, F., Leonard, D., (2008). Characterization of TBP containing polysiloxane membrane/insulator/semiconductor structures for hexavalent chromium detection Materials Science and Engineering: C-Biomimetic and Supramolecular Systems Elsevier Science BV 285-6, 1014-1019

Errachid, A., Mills, C. A., Pla-Roca, M., Lopez, M. J., Villanueva, G., Bausells, J., Crespo, E., Teixidor, F., Samitier, J., (2008). Focused ion beam production of nanoelectrode arrays Materials Science & Engineering C Elsevier Science 285-6, 777-780

Casuso, I., Pla-Roca, M., Gomila, G., Samitier, J., Minic, J., Persuy, M. A., Salesse, R., Pajot-Augy, E., (2008). Immobilization of olfactory receptors onto gold electrodes for electrical biosensor Materials Science & Engineering C Elsevier Science 285-6, 686-691

Castellarnau, M., Zine, N., Bausells, J., Madrid, C., Juarez, A., Samitier, J., Errachid, A., (2008). ISFET-based biosensor to monitor sugar metabolism in bacteria Materials Science & Engineering C Elsevier Science 285-6, 680-685

Barhoumi, H., Haddad, R., Maaref, A., Bausells, J., Bessueille, F., Leonard, D., Jaffrezic-Renault, N., Martelet, C., Zine, N., Errachid, A., (2008). Na+-implanted membrane for a capacitive sodium electrolyte-Insulator-Semiconductor microsensors Sensor Letters Amer Scientific Publishers 61, 204-208

Sabella, C., Faszewski, E., Himic, L., Colpitts, K. M., Kaltenbach, J., Burger, M. M., Fernàndez-Busquets, X., (2007). Cyclosporin A suspends transplantation reactions in the marine sponge Microciona prolifera Journal of Immunology 1799, 5927-5935

Pla-Roca, M., Fernandez, J. G., Mills, C. A., Martinez, E., Samitier, J., (2007). Micro/nanopatterning of proteins via contact printing using high aspect ratio PMMA stamps and NanoImprint apparatus Langmuir 2316, 8614-8618

Mills, C. A., Pla-Roca, M., Martin, C., Lee, M., Kuphal, M., Sisquella, X., Martinez, E., Errachid, A., Samitier, J., (2007). Structured thin organic active layers and their use in electrochemical biosensors Measurement & Control 403, 88-91

Rodriguez, Segui, Bucior, I., Burger, M. M., Samitier, J., Errachid, A., Fernandez-Busquets, X., (2007). Application of a bio-QCM to study carbohydrates self-interaction in presence of calcium Transducers '07 & Eurosensors Xxi, Digest of Technical Papers IEEE 1-2, 1995-1998

Jbari, A., Bellarbi, L., Zine, N., Mills, C. A., Samitier, J., Errachid, A., (2007). Multiplexed frequency spectrum analyzer instrumentation for the characterization of multiple QCM-based biosensors C3 - 2007 SENSORCOMM 2007 IEEE , 436-440

McMurray, A. A., Ali, Z., Kyselovik, J., Mills, C. A., Renault, N. J., Santha, H., Strohhöfer, C., (2007). A novel point of care diagnostic device: Impedimetric detection of a biomarker in whole blood EMBS 2007 IEEE , 115-118

Castellarnau, Marc, Errachid, Abdelhamid, Madrid, Cristina, Juárez, Antonio, Samitier, Josep, (2006). Dielectrophoresis as a tool to characterize and differentiate isogenic mutants of Escherichia coli Biophysical Journal 9110, 3937-3945

Muñoz, Luis Miguel, Casals, Alícia, Amat, Josep, Puig-Vidal, Manel, Samitier, Josep, (2005). Improved AFM scanning methodology with adaptation to the target shape C3 - Proceedings - IEEE International Conference on Robotics and Automation ICRA 2005 IEEE , 1529-1534

Equipment

Nanofabrication and nanomanipulation

  • Automatized microcontact printing system (custom-made)
  • Dip-Pen Nanolithography system (DPN)
  • Nanoplotter NPM
  • Nanotechnology Platform (PCB): equipment for hot embossing lithography, polymer processing and photolithography, chemical wet etching, e-beam evaporation

Characterization

  • Surface Plasmon Resonance (SPR)
  • Quartz crystal microbalance (QCM)
  • Optical Waveguide Lightmode Spectroscope (OWLS)
  • Atomic Force Microscope (AFM)
  • Optical Microscopes (white light/epifluorescence)
  • Impedance spectroscopes
  • Precision Impedance Analyzer
  • Sub-femtoamp Remote SourceMeter Instrument

Molecular/cell biology

  • Biological safety cabinet (class II)
  • Microwell plate readers
  • Protein and DNA electrophoresis systems
  • Nanodrop spectrophotometer

Microfluidics laboratory

  • High precision syringe pumps
  • Peristaltic pumps

Collaborations

 

  • Microfluidic ChipShop GmbH
  • Prof. Barbara Mazzolai IIT Center for Micro-BioRobotics (CMBR), Pontedera, Italy
  • Prof. Josep Maria Canals University of Barcelona, Spain
  • Dr. José Antonio Andrades Universidad de Málaga, Spain
  • Prof. Fernando Albericio Institut de Recerca Biomédica (IRB), Barcelona, Spain
  • Tallers Fiestas S.L.
  • Enantia S.L.
  • Biokit S.A. (Werfen group)
  • Genomica S.A.U. (Zeltia group)
  • Prof. Ramón Eritja Institut de Recerca Biomédica (IRB), Barcelona (Spain)
  • Dr. Hernando del Portillo Centro de Investigación en Salud Internacional de Barcelona (CRESIB), Barcelona (Spain)
  • Prof. Andre Bernard MNT- NTB, Buchs, Switzerland
  • Prof. Daniel Riveline ISIS/IGBMC, Strasbourg
  • Prof. Albert van den Berg University of Twente (The Netherlands)
  • Dr. Jaume Reventós Hospital Vall d’Hebrón, Barcelona (Spain)
  • Dr. Juan C. Izpisúa CMRB, Barcelona (Spain)
  • Dr. Mª Pilar Marco IIQAB-CSIC, Barcelona (Spain)
  • Dr. M. Lluïssa Pérez Dept. Farmacología, University of Barcelona (Spain)
  • Prof. Joan Bausells CNM-CSIC, Barcelona (Spain)
  • Prof. Vasco Teixeira Universidade do Minho, Braga (Portugal)
  • Prof. Jean-Louis Marty Université de Perpignan Via Domitia (France)
  • Dr. Nicole Jaffrezic Université Claude Bernard Lyon 1 (France)
  • Dr. Matthew Dalby University of Glasgow (UK)
  • Prof. Molly M. Stevens Imperial College, London (UK)
  • Dr. Graham Johnson Uniscan Instruments Ltd, Buxton (UK)
  • Prof. G. Fuhr FhG Biomedicine, St. Ingbert, Germany
  • Dr. Max M. Burger Novartis AG, Switzerland, and Marine Biological Laboratory, Woods Hole, USA
  • Prof. D. Anselmetti Universität Bielefeld, Germany
  • Prof. François Rossi JRC – ISPRA
  • Prof. M. Madou University of California at Irvine, USA
  • Prof. M. Sampietro Politecnico di Milano, Italy
  • Prof. H. Börner Max-Planck Institute of Colloids and Interfaces, Golm, Germany
  • Prof. Paolo Dario Center for Micro-BioRobotics IIT@SSSA, Pisa, Italy
  • Dr. Edith Pajot INRA, France
  • Dr. Christophe Vieu LAAS-CNRS Toulouse, France
  • Prof. E. Faszewski Wheelock College, Boston, USA
  • Prof. L. Reggiani INFM, Nanotechnology Laboratory, Lecce, Italy

 

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