BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Institute for Bioengineering of Catalonia - ECPv6.3.5//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Institute for Bioengineering of Catalonia X-ORIGINAL-URL:https://ibecbarcelona.eu/ca/ X-WR-CALDESC:Esdeveniments per Institute for Bioengineering of Catalonia REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:Europe/Madrid BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20200329T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20201025T010000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20200224T113000 DTEND;TZID=Europe/Madrid:20200224T133000 DTSTAMP:20240328T185702 CREATED:20200205T152838Z LAST-MODIFIED:20200205T154515Z UID:71057-1582543800-1582551000@ibecbarcelona.eu SUMMARY:PhD Thesis Defence: Martí Checa DESCRIPTION:A Novel Scanning Probe Microscopy technique to study the nanoscale electrical properties of cells\nMartí Checa\, Nanoscale bioelectrical characterization group \nThe goal of this work of thesis is the study of electrical properties in cells. That is the study of how they can conduct electricity\, accumulate charges\, or polarize. Experimental techniques able to measure electrical properties of complex heterogeneous samples (like cells) with excellent spatial resolution are needed to accomplish such characterization at the single-cell level (microscale) or even at the subcellular level (nanoscale). During this work of thesis\, a new experimental technique named “Scanning Dielectric Force Volume Microscopy (SDFVM)” has been developed together with the theoretical modeling for its understanding when operated in a liquid environment. \nThe technique has been validated with known samples (both in dry and liquid) and applied to many different nanometric systems of interest. The first full map of the local dielectric constant of a prokaryotic cell in dry conditions has been obtained with unparalleled accuracy and spatial resolution\, demonstrating its capability for label-free composition and structural mapping. Moreover\, the method has been applied to liquid environment\, obtaining the first-ever local dielectric contrast in fixed eukaryotic cells. Furthermore\, the first preliminary results in living cells have also been shown. SDFVM is expected to have an important impact not only in Life Sciences but also in Material Science\, where the mapping of the dielectric properties of samples showing complex nanoscale topographies is often needed. \n  \n  \n  \nShare this...FacebookPinterestTwitterLinkedin URL:https://ibecbarcelona.eu/ca/event/phd-thesis-defence-marti-checa/ LOCATION:Eduard Fontseré – Facultat de Física de la UB CATEGORIES:PhD Thesis Defence END:VEVENT END:VCALENDAR