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by Keyword: Safety


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Berges, E., Casals, A., (2014). Considering civil liability as a safety criteria for cognitive surgical robots IFMBE Proceedings XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013 (ed. Roa Romero, Laura M.), Springer International Publishing (London, UK) 41, 113-116

One of the challenges of the robotics community is to develop robots that behave more and more autonomously. Therefore, it is necessary to establish new design criteria, as well as more complex methodologies supporting the analysis of associated risks. The procedure described in this paper includes civil liability as an additional criterion to validate the safety of a surgical robot. In order to understand the concept, a methodology is presented through the description of a simple case. This work aims to establish the basis for a further implementation.

Keywords: Design methodology, Product development, Product liability, Safety, Robotic surgery, Cognitive robotics


Tort, N., Salvador, J. P., Eritja, R., Poch, M., Martinez, E., Samitier, J., Marco, M. P., (2009). Fluorescence site-encoded DNA addressable hapten microarray for anabolic androgenic steroids Trac-Trends in Analytical Chemistry , 28, (6), 718-728

We report a new strategy for immunochemical screening of small organic molecules based on the use of a hapten microarray. Using DNA-directed immobilization strategies, we have been able to convert a DNA chip into a hapten microarray by taking advantage of all the benefits of the structural and electrostatic homogeneous properties of DNA. The hapten microarray uses hapten-oligonucleotide probes instead of proteins, avoiding the limitations of preparing stochiometrically-defined protein-oligonucleotide bioconjugates. As proof of concept, we show here the development of a microarray for analysis of anabolic androgenic steroids. The microchip is able to detect several illegal substances with sufficient detectability to be used as a screening method, according to the regulations of the World Anti-Doping Agency for sport and the European Commision for food safety. The results that we show corroborate the universal possibilities of the DNA chip, and, in this case, they open the way to develop hapten microarrays for the immunochemical analysis of small organic molecules.

Keywords: Anti-doping, DNA chip, DNA-directed immobilization (DDI), Fluorescence, Food safety, Hapten microarray, Immunochemical screening, Proof of concept, Small organic molecule, Steroid